Current Challenges in the Design of Effective Antifungal Surfaces (Poster)


(Work is copyright Bryan Coad, 2014)

I presented this poster at the Australasian Society for Infectious Diseases (ASID) conference earlier this year.

I’m making it available for download for personal/educational use.

Clicking here will link to a PDF download (2 MB) of the full sized poster. The poster is copyrighted and not for reproduction. If you intend to use this work for personal/educational use, please contact me and I will provide a non-watermarked PDF copy.

Further Investigations of Gradient Polymer Brush Surfaces — New Publication

We have just published another study on polymer brush gradients in Langmuir.

Polymer Brush Gradients Grafted from Plasma-Polymerized Surfaces

Gradient polymer brush

Published in: Bryan R. Coad; Tugba Bilgic; Harm-Anton Klok; Langmuir  Article ASAP DOI: 10.1021/la501380m Copyright © 2014 American Chemical Society

This work describes a 3 step method for grafting polymer brushes from any substrate. Subsequent work (which happened to be accepted and published first) shows a 2 step method (see post here).

These two works show good understanding of different systems.  First, two different plasma polymer gradients were fabricated based on octadiene/allylamine and ethanol/ethylisobromobutyrate, and polymer grafting was shown for hydroxyethyl methacrylate (HEMA), dimethyl acrylamide (DMA), and poly(ethyleneglycol) methacrylate (PEGMA).  Last, we have show in this work gradient brushes grown from silicon wafers, and previously, from plastic coverslips.

I was especially pleased with this work as it gave me an opportunity to work with Prof. Harm-Anton Klok from EPFL in Switzerland.  Prof. Klok’s work was an inspiration for me during my PhD and I am very glad to have the chance to work with him in a nice collaboration.

Many thanks goes to him and his student, Tugba Bilgic, for helping me with this work.

Antibacterial Surfaces from Chlorinated Plasma Polymers

Just published communication in RSC Advances.

plasma polymerization of 1,1,1-trichloroethane yields coating with robust antibacterial surface properties

A new study published from the Mawson Institute and the Wark at UniSA and QUT reveals how a straightforward plasma deposition of an inexpensive compound leads to effective antibacterial surfaces.

Chlorinated surfaces rapidly kill Staphylococcus epidermidis on contact.  The action occurs rapidly and there is little difference if the prepared surface is dry, wet or washed.

Read more about this research here.

Copper from seawater can be selectively bound and accumulated into PEI films

Just published in RSC Advances, a new paper from work I did with Johan Linden, Mikael Larsson, Bill Skinner, and Magnus Nyden:

Polyethyleneimine for copper absorption: kinetics, selectivity and efficiency in artificial seawater

image copyright Royal Society of Chemistry

image copyright Royal Society of Chemistry

Link to paper in RSC Advances

The surprising result was that a simple, industrial polymer was so effective at first binding metal ions but then, over time, having a greater affinity only for copper leaving the film to be enriched only in this metal.

Thus, copper can be scavenged selectively from low concentration seawater solutions.  This has implications for removal of toxic copper from marinas — an environmental problem caused by leaching of copper from antifouling marine coatings.


New article in ACS Applied Materials and Interfaces

One Step ATRP Initiator Immobilization on Surfaces Leading to Gradient-Grafted Polymer Brushes

by Bryan Coad, Katie Styan and Laurence Meagher

Just came out in ASAP (as soon as publishable)


Image copyright the American Chemical Society

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